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All about: Grifulvin V

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Generic Name: griseofulvin (gris e o FULL vin)
Brand Names: Fulvicin P/G, Fulvicin U/F, Grifulvin V, Gris-PEG, Grisactin 250, Grisactin 500, Grisactin Ultra

What is Grifulvin V (griseofulvin)?

Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Griseofulvin is used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete's foot, and barber's itch.

Griseofulvin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Grifulvin V (griseofulvin)?

Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Avoid prolonged exposure to sunlight. Griseofulvin increases sensitivity to sunlight, and severe burning may result.

What should I discuss with my healthcare provider before taking Grifulvin V (griseofulvin)?

You cannot take griseofulvin if you

  • have ever had an allergic reaction to it,

  • have porphyria, or

  • have liver disease.

Talk to your doctor before taking griseofulvin if you have any of the conditions listed above.

Griseofulvin is in the FDA pregnancy category C. This means that it is not known whether griseofulvin will harm an unborn baby. In rare cases, the use of griseofulvin has been associated with conjoined twins. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether griseofulvin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Griseofulvin may affect sperm and sperm production. It is recommended that you avoid fathering a child during treatment with griseofulvin and for 6 months following therapy.

How should I take Grifulvin V (griseofulvin)?

Take griseofulvin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass (8 ounces) of water. Your doctor may recommend that you take griseofulvin with a fatty meal to increase its absorption into your body. Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of griseofulvin with a dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Store griseofulvin tablets, capsules, and suspension at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Take the rest of the day's doses at evenly spaced intervals unless your doctor directs otherwise.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a griseofulvin overdose are not well known but might include nausea, vomiting, diarrhea, headache, numbness and tingling, and confusion.

What should I avoid while taking Grifulvin V (griseofulvin)?

Avoid prolonged exposure to sunlight. Griseofulvin increases sensitivity to sunlight, and severe burning may result. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. The combination of alcohol and griseofulvin may cause flushing and a fast heart rate. Use alcohol cautiously during treatment with griseofulvin.

Grifulvin V (griseofulvin) side effects

Stop taking griseofulvin and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take griseofulvin and notify your doctor if you experience

  • white patches in your mouth (thrush/yeast infection);

  • nausea, vomiting, or diarrhea;

  • headache, dizziness, or tiredness;

  • insomnia;

  • confusion;

  • numbness or tingling in your hands or feet; or

  • menstrual irregularities.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Grifulvin V (griseofulvin)?

Griseofulvin may decrease the effects of the following drugs:

  • oral anticoagulants (blood thinners) such as warfarin (Coumadin). A decrease in the effectiveness of anticoagulants could lead to blood clotting. It may be necessary to increase anticoagulant dosage.

  • birth control pills. Decreased effectiveness could lead to break-through bleeding and possibly to an unintended pregnancy. Talk to your doctor about using of other forms of birth control during treatment with griseofulvin.
  • salicylates such as aspirin, salsalate (Disalcid, Salsitab, Salflex, others), choline salicylate (Arthropan), magnesium salicylate (Doan's, Magan), and others. Larger doses of these medicines may be needed.

  • cyclosporine (Sandimmune, Neoral). Your doctor may need to adjust your cyclosporine dosage.

The effects of griseofulvin may be decreased by barbiturates such as phenobarbital (Luminal, Solfoton), pentobarbital (Nembutal), secobarbital (Seconal), amobarbital (Amytal), and butabarbital (Butisol). Larger doses of griseofulvin may be necessary if you are taking any of these drugs.

Drugs other than those listed here may also interact with griseofulvin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Where can I get more information?

  • Your pharmacist has additional information about griseofulvin written for health professionals that you may read.

What does my medication look like?

Griseofulvin is available with a prescription under several brand and generic names. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Fulvicin U/F 250 mg--round, white tablets

  • Fulvicin U/F 500 mg--round, white tablets

  • Fulvicin P/G 125 mg--round, white tablets

  • Fulvicin P/G 165 mg--oval, off-white tablets

  • Fulvicin P/G 250 mg--round, white tablets

  • Fulvicin P/G 330 mg--oval, off-white tablets

  • Grifulvin V 250 mg--round, white tablets

  • Grifulvin V 500 mg--round, white tablets

  • Grifulvin V Suspension--125 mg/5 mL

  • Grisactin 125 mg--capsules

  • Grisactin 250 mg--yellow capsules

  • Grisactin 500 mg--round, pink tablets

  • Grisactin Ultra 125 mg--square, white tablets

  • Grisactin Ultra 250 mg--square, white tablets

  • Grisactin Ultra 330 mg--oval, white tablets

  • Gris-PEG 125 mg--elliptical, white tablets

  • Gris-PEG 250 mg--capsule-shaped, white tablets

  • Remember, keep this and all other medicines out of the reach of children. Never share your medicines with others and only use this medicine for the illness your doctor prescribed it for.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 2.07. Revision Date: 8/2/04 3:40:04 PM.

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