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All about: Guaifenesin/Pseudoephedrine Capsules

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Generic Name: Guaifenesin/Pseudoephedrine Capsules (gwye-FEN-ah-sin/sue-do-eh-FED-rin)
Brand Name: Examples include Robitussin Severe Congestion and Sinutab Non-Drying

Guaifenesin/Pseudoephedrine Capsules is used for:

Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Guaifenesin/Pseudoephedrine Capsules is a decongestant and expectorant combination. It works by constricting blood vessels, reducing swelling in the nasal passages, and thinning and loosening mucus. This allows you to breathe more easily and makes coughs more productive.

Do NOT use Guaifenesin/Pseudoephedrine Capsules if:

  • you are allergic to any ingredient in Guaifenesin/Pseudoephedrine Capsules
  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Guaifenesin/Pseudoephedrine Capsules:

Some medical conditions may interact with Guaifenesin/Pseudoephedrine Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a fast, slow, or irregular heartbeat
  • if you have a history of adrenal gland problems (eg, tumor), heart problems, high blood pressure, diabetes, heart blood vessel problems, stroke, glaucoma, an enlarged prostate, seizures, or an overactive thyroid
  • if you have chronic cough

Some MEDICINES MAY INTERACT with Guaifenesin/Pseudoephedrine Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Guaifenesin/Pseudoephedrine Capsules may be increased
  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine because the risk of side effects may be increased by Guaifenesin/Pseudoephedrine Capsules
  • Guanethidine, guanadrel, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Guaifenesin/Pseudoephedrine Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Guaifenesin/Pseudoephedrine Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Guaifenesin/Pseudoephedrine Capsules:

Use Guaifenesin/Pseudoephedrine Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Guaifenesin/Pseudoephedrine Capsules may be taken with or without food.
  • Take Guaifenesin/Pseudoephedrine Capsules with a full glass of water unless otherwise directed by your doctor.
  • If you miss a dose of Guaifenesin/Pseudoephedrine Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Guaifenesin/Pseudoephedrine Capsules.

Important safety information:

  • Guaifenesin/Pseudoephedrine Capsules may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Guaifenesin/Pseudoephedrine Capsules. Using Guaifenesin/Pseudoephedrine Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Do not take appetite suppressants while you are taking Guaifenesin/Pseudoephedrine Capsules without checking with your doctor.
  • Guaifenesin/Pseudoephedrine Capsules contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.
  • Do NOT exceed the recommended dose or take Guaifenesin/Pseudoephedrine Capsules for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
  • Guaifenesin/Pseudoephedrine Capsules may interfere with certain lab test results. Make sure that all of your doctors and laboratory personnel know that you are taking Guaifenesin/Pseudoephedrine Capsules.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Guaifenesin/Pseudoephedrine Capsules.
  • Use Guaifenesin/Pseudoephedrine Capsules with caution in the ELDERLY because they may be more sensitive to its effects.
  • Caution is advised when using Guaifenesin/Pseudoephedrine Capsules in CHILDREN because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Guaifenesin/Pseudoephedrine Capsules, discuss with your doctor the benefits and risks of using Guaifenesin/Pseudoephedrine Capsules during pregnancy. It is unknown if Guaifenesin/Pseudoephedrine Capsules is excreted in breast milk. Do not breast-feed while taking Guaifenesin/Pseudoephedrine Capsules.

Possible side effects of Guaifenesin/Pseudoephedrine Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; and vomiting.

Proper storage of Guaifenesin/Pseudoephedrine Capsules:

Store Guaifenesin/Pseudoephedrine Capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Guaifenesin/Pseudoephedrine Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Guaifenesin/Pseudoephedrine Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Guaifenesin/Pseudoephedrine Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Guaifenesin/Pseudoephedrine Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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