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All about: Methenamine/Sodium Biphosphate

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Generic Name: Methenamine/Sodium Biphosphate Tablets (meth-EN-ah-meen/so-DEE-um bye-FOS-fate)
Brand Name: Uroqid-Acid No. 2

Methenamine/Sodium Biphosphate is used for:

Preventing and treating urinary tract infections.

Methenamine/Sodium Biphosphate is a urinary antiseptic and urinary acidifier combination. It works by concentrating in the urine as formaldehyde, which kills bacteria in the urine.

Do NOT use Methenamine/Sodium Biphosphate if:

  • you are allergic to any ingredient in Methenamine/Sodium Biphosphate
  • you have kidney problems, too much phosphate in your blood, or you are severely dehydrated
  • you are taking a sulfonamide (eg, sulfamethizole)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Methenamine/Sodium Biphosphate :

Some medical conditions may interact with Methenamine/Sodium Biphosphate . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you are on a low-salt diet
  • if you have a fever or chills, diarrhea, a stomach infection, toxemia of pregnancy, liver problems, or gout
  • if you have a history of heart problems, swelling, high blood pressure, pancreatitis, thyroid problems, or electrolyte problems

Some MEDICINES MAY INTERACT with Methenamine/Sodium Biphosphate . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Sulfonamides (eg, sulfamethizole) because the effectiveness of Methenamine/Sodium Biphosphate may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methenamine/Sodium Biphosphate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Methenamine/Sodium Biphosphate :

Use Methenamine/Sodium Biphosphate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Methenamine/Sodium Biphosphate with food if it upsets your stomach.
  • Before you begin using an antacid, check with your doctor or pharmacist.
  • If you miss a dose of Methenamine/Sodium Biphosphate , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Methenamine/Sodium Biphosphate .

Important safety information:

  • Methenamine/Sodium Biphosphate may interfere with certain lab test results. Be sure your doctors and lab professionals know you are taking Methenamine/Sodium Biphosphate .
  • LAB TESTS, including urine pH, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: It is unknown if Methenamine/Sodium Biphosphate can cause harm to the fetus. If you become pregnant while taking Methenamine/Sodium Biphosphate , discuss with your doctor the benefits and risks of using Methenamine/Sodium Biphosphate during pregnancy. Methenamine/Sodium Biphosphate is excreted in breast milk. If you are or will be breast-feeding while you are using Methenamine/Sodium Biphosphate , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Methenamine/Sodium Biphosphate :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; upset stomach.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; joint pain; mental/mood changes; muscle cramps; numbness or tingling of lips, hands, or feet; seizures; unusual thirst; unusual weakness; unusual weight gain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center ( http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Methenamine/Sodium Biphosphate :

Store Methenamine/Sodium Biphosphate at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Methenamine/Sodium Biphosphate out of the reach of children and away from pets.

General information:

  • If you have any questions about Methenamine/Sodium Biphosphate , please talk with your doctor, pharmacist, or other health care provider.
  • Methenamine/Sodium Biphosphate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Methenamine/Sodium Biphosphate . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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