23 . October , 2018 - Tuesday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Nebcin

Big Image
Generic Name: Tobramycin Injection (toe-bra-MYE-sin)
Brand Name: Nebcin

Nebcin has caused kidney problems, nerve damage or permanent hearing loss, even at usual doses. Hearing loss can occur even after the medicine is stopped. If you already have kidney problems or hearing difficulty, tell your doctor. Notify your doctor immediately if any of the following occur: ringing in ears, hearing loss, unusual change in amount of urine, dizziness, numbness, skin tingling, muscle twitching, or seizures. Nebcin may be stopped if you develop kidney or hearing problems. Your doctor will monitor your progress to minimize the possibility of these effects occurring and to run certain tests (eg, hearing and/or kidney tests). Do not use Nebcin with other medicines that can cause nerve, kidney, or hearing problems. Other factors that increase the risk of these side effects occurring include premature and newborn infants, advanced age, or dehydration. Avoid other medicines that may harm the kidney or decrease hearing (eg, other aminoglycosides [eg, gentamicin], cephaloridine, viomycin, polymyxin B, colistin, cisplatin, vancomycin) while you are using Nebcin . Do not use Nebcin with certain diuretics (eg, furosemide, ethacrynic acid).

Nebcin may cause fetal harm if used during pregnancy.


Nebcin is used for:

Treating serious infections caused by certain bacteria.

Nebcin is an aminoglycoside antibiotic. It works by killing sensitive bacteria.

Do NOT use Nebcin if:

  • you are allergic to any ingredient in Nebcin or another aminoglycoside antibiotic (eg, gentamicin)
  • you are taking certain diuretics (eg, furosemide, ethacrynic acid), cyclosporine, methoxyflurane, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nebcin :

Some medical conditions may interact with Nebcin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have myasthenia gravis (a condition in which the muscles become progressively paralyzed) or Parkinson disease
  • if you have dehydration, hearing problems, nerve problems, kidney problems, or severe or extensive burns

Some MEDICINES MAY INTERACT with Nebcin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Beta-lactam antibiotics (eg, penicillin, imipenem, ceftizoxime) because effectiveness of Nebcin may be decreased
  • Cephaloridine, cephalosporins (eg, ceftizoxime), cisplatin, colistin, cyclosporine, fludarabine, loop diuretics (eg, furosemide, ethacrynic acid), methoxyflurane, nitrosoureas (eg, carmustine), NSAIDs (eg, ibuprofen), polymyxin B, vancomycin, or viomycin because they may increase the risk of Nebcin 's side effects, including increased risk of kidney or hearing loss
  • Nondepolarizing muscle relaxants (eg, atracurium) or succinylcholine because the risk of their side effects may be increased by Nebcin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nebcin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nebcin :

Use Nebcin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Nebcin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Nebcin at home, a health care provider will teach you how to use it. Be sure you understand how to use Nebcin . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Nebcin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Nebcin , use it as soon as possible. Check with your doctor or pharmacist for instructions on scheduling other doses.

Ask your health care provider any questions you may have about how to use Nebcin .

Important safety information:

  • Nebcin only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Drinking extra fluids while you are using Nebcin is recommended. Check with your doctor for instructions.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Be sure to use Nebcin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Nebcin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Tell your doctor or dentist that you take Nebcin before you receive any medical or dental care, emergency care, or surgery.
  • Lab tests, including kidney function, hearing tests, and tobramycin levels, may be performed while you use Nebcin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Nebcin with caution in the ELDERLY; they may be more sensitive to its effects, especially kidney or hearing problems.
  • Nebcin should be used with extreme caution in CHILDREN younger than 10 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Nebcin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nebcin while you are pregnant. It is not known if Nebcin is found in breast milk after inhalation. Do not breast-feed while taking Nebcin .

Possible side effects of Nebcin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; headache; nausea; pain, swelling, or redness at the injection site; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); clumsiness; confusion; decreased hearing; decreased urination; dizziness or lightheadedness; feeling of a whirling motion; fever; hearing loss; itching; muscle weakness; numbness or tingling; ringing or roaring in the ears; seizures; unusual bruising or bleeding; vaginal irritation or discharge.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms include decreased urination; dizziness; hearing loss; trouble breathing.

Proper storage of Nebcin :

This medicine is usually handled and stored by a health care provider. If you are using Nebcin at home, store Nebcin as directed by your pharmacist or health care provider. Keep Nebcin , as well as syringes and needles, out of the reach of children and away from pets.

General information:

  • If you have any questions about Nebcin , please talk with your doctor, pharmacist, or other health care provider.
  • Nebcin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Nebcin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

Recent Drug Updates at DrugIndexOnline:





Amyl Nitrite Amyl Nitrite
Generic name product may be available in the U.S. and Canada. Category Antianginal Antidote to cyanide poisoning Diagnostic aid, cardiac function Description Amyl nitrite (AM-il NYE-trite) is related to the nitrate medicines and is used by inhalation to relieve the pain of angina attacks. I more...

Anastrozole Anastrozole
Pronouncation: (an-ASS-troe-zole) Class: Aromatase inhibitor Trade Names: Arimidex - Tablets for oral use 1 mg Mechanism of Action Pharmacology A selective nonsteroidal aromatase inhibitor. It lowers serum estradiol concentrations. Pharmacokinetics Distribution 40% protein bound. Metabolism Metabol more...

Claritin-D 12 Hour Claritin-D 12 Hour
Some commonly used brand names are: In the U.S.— Allerest Maximum Strength 7 Allerphed 14 Atrohist Pediatric 7 Atrohist Pediatric Suspension Dye Free 8 Benadryl Allergy Decongestant Liquid Medication 10 Brofed Liquid 3 Bromadrine TR 3 Bromfed 3 Bromfed-PD 3 Bromfenex 3 Bromfenex PD 3 Chlo more...

Diaper Rash Ointment Topical Diaper Rash Ointment Topical
Some commonly used brand names are: In the U.S.— Calamox In Canada— Diaper Rash Ointment Onguent de Calamine Generic name product may be available in the U.S. and Canada. Category Antipruritic, topical Skin protectant Description Calamine (KAL-a-meen) is used to relieve t more...

Diulo Diulo
Some commonly used brand names are: In the U.S.— Aquatensen 6 Diucardin 5 Diulo 7 Diuril 2 Enduron 6 Esidrix 4 Hydro-chlor 4 Hydro-D 4 HydroDIURIL 4 Hydromox 9 Hygroton 3 Metahydrin 10 Microzide 4 Mykrox 7 Naqua 10 Naturetin 1 Oretic 4 Renese 8 Saluron 5 Thalitone 3 Trichlorex 10 Zaroxoly more...

Dolotic Dolotic
Generic Name: Antipyrine/Benzocaine (an-tee-PYE-reen/BEN-zoe-kane) Brand Name: Examples include Aurodex and DoloticDolotic is used for:Relieving pain and inflammation in the ear caused by various conditions. It may be used with antibiotics given by mouth to treat middle ear infections. It may more...

Kionex Kionex
Generic Name: sodium polystyrene sulfonate Dosage Form: Powder, for suspension Cation-Exchange Resin Kionex Description Kionex® brand of sodium polystyrene sulfonate is a benzene, diethenyl- polymer with ethenylbenzene, sulfonated, sodium salt and has the following structural formula: The more...

Metronidazole Cream Metronidazole Cream
Generic Name: Metronidazole Cream, Gel, and Lotion (me-troe-NIH-duh-zole) Brand Name: Examples include MetroCream, MetroGel, and MetroLotionMetronidazole Cream is used for:Treating redness and inflammation associated with the skin disorder rosacea. It also may be used for other conditions as d more...