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All about: Norditropin

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Generic Name: Somatropin (rDNA origin - Refrigerated) (Norditropin) (soe-ma-TROE-pin)
Brand Name: Norditropin

Norditropin is used for:

Treating certain children or adults when the body does not produce enough growth hormone. It may also be used for other conditions as determined by your doctor.

Norditropin is a growth hormone that produces effects that are identical to the body's naturally occurring growth hormone. It affects the growth of bones, muscles, internal organs, and other tissues of the body.

Do NOT use Norditropin if:

  • you are allergic to any ingredient in Norditropin
  • you have or are currently being treated for cancer or any unusual growths or tumors (especially in the brain) that may still be growing
  • you have vision problems due to diabetes (diabetic retinopathy), premature epiphyseal closure (your bone growth is complete) or a serious illness caused by complications from surgery, trauma, or severe breathing problems (eg, respiratory failure)
  • you have Prader-Willi syndrome and are severely overweight or have severe breathing problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Norditropin :

Some medical conditions may interact with Norditropin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have endocrine problems including pituitary or adrenal gland problems, diabetes or a family history of diabetes, or an underactive thyroid
  • if you have a history of leukemia, unusual growths or tumors (especially in the brain), or cancer
  • if you have curvature of the spine (scoliosis), kidney or liver problems, Prader-Willi syndrome, are severely overweight, or have had recent major surgery or trauma

Some MEDICINES MAY INTERACT with Norditropin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anticonvulsants (eg, phenytoin, carbamazepine) or cyclosporine because side effects may be increased or effectiveness may be decreased by Norditropin
  • Corticosteroids (eg, prednisone) because effectiveness of Norditropin may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Norditropin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Norditropin :

Use Norditropin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Norditropin is sometimes used at home as an injection. Before you use Norditropin , a health care provider will provide detailed instructions for its appropriate use. Ask any questions that you may have about Norditropin or giving injections.
  • If you are using Norditropin at home, carefully follow the injection procedures taught to you by your health care provider. If the medicine contains particles, is discolored, or if the vial/container is cracked or damaged in any way, do not use it.
  • Always change the location where you inject Norditropin .
  • Do not shake Norditropin . Swirl the vial gently to mix it.
  • If you miss a dose of Norditropin , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Norditropin .

Important safety information:

  • Norditropin may cause dizziness. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity.
  • Never reuse needles and syringes. Follow your health care provider's instructions for proper disposal of needles and syringes. Ask your health care provider or pharmacist to explain local regulations for selecting an appropriate container and properly disposing of the container when it is full.
  • Norditropin may contain benzyl alcohol, metacresol, or glycerin. Tell your doctor if you have ever had sensitivity or an allergic reaction to benzyl alcohol, metacresol, or glycerin.
  • Diabetes patients - Norditropin may affect your blood sugar levels. Check your blood sugar levels closely and ask your doctor before adjusting your diabetes medicine or changing your diet.
  • LAB TESTS may be required to monitor therapy. Be sure to keep appointments.
  • ELDERLY patients may be more sensitive to the effects of Norditropin .
  • Rare, sometimes fatal, lung and breathing problems may be caused by Norditropin in CHILDREN with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or children with existing serious lung or breathing problems. Children should be checked for certain breathing problems before and during treatment. If your child develops a limp or complains of hip or knee pain during treatment with Norditropin , contact your doctor immediately. Tell your doctor immediately if your child becomes very sick or is hospitalized while using Norditropin . Norditropin may need to be stopped.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss the benefits and risks of using Norditropin during pregnancy with your doctor. It is unknown if Norditropin is excreted in breast milk. If you plan to breast-feed while you are using Norditropin , talk with your doctor about the risks to your baby.

Possible side effects of Norditropin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bone pain; headache; increased sweating; mild flu-like symptoms; mild swelling (eg, of the hands or feet); muscle or joint pain; nerve tingling; redness or itching at the injection site; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); body pain or stiffness; burning, tingling, itching, or numbness in the palm of the hand, fingers, or wrist; change in appearance or size of a mole; chest pain; constant feeling of need to empty the bowel; curvature of the spine; depression; ear infection; excessive thirst or hunger; fast heartbeat; fever; frequent urination; increased pressure in the head or eye; infection; nausea; severe or persistent swelling of the ankles, legs, hands, or feet; severe, persistent, or unusual headache; stomach pain; visual changes; vomiting.

Children: Ear discomfort or infection; fatigue or weakness; fever, persistent cough, or trouble breathing; hip or knee pain; leukemia; limp; seizures; snoring or irregular breathing during sleep; worsening of psoriasis.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include: excessive thirst or hunger; frequent urination; headache; nausea or vomiting; swelling of the ankles, feet, or hands.

Proper storage of Norditropin :

Before mixing, store Norditropin in the refrigerator at 36 to 46 degrees F (2 to 8 degrees C). Do not freeze. Protect from light. Do not use Norditropin past the expiration date on the product label. After mixing, store Norditropin according to the product label. Contact your pharmacist if you have any questions about the proper storage of Norditropin . Keep Norditropin , as well as needles and syringes, out of the reach of children and away from pets.

General information:

  • If you have any questions about Norditropin , please talk with your doctor, pharmacist, or other health care provider.
  • Norditropin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Norditropin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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