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All about: Acetazolamide Sustained-Release Capsules

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Generic Name: Acetazolamide Sustained-Release Capsules (a-set-a-ZOLE-a-mide)
Brand Name: Diamox Sequels

Acetazolamide Sustained-Release Capsules is used for:

Treating certain types of glaucoma in combination with other medicines. It is also used to treat or prevent symptoms of mountain sickness. It may also be used to treat other conditions as determined by your doctor.

Acetazolamide Sustained-Release Capsules is a carbonic anhydrase inhibitor. It reduces fluid pressure in the eyeball by decreasing fluid formation in the eyeball.

Do NOT use Acetazolamide Sustained-Release Capsules if:

  • you are allergic to any ingredient in Acetazolamide Sustained-Release Capsules
  • you have adrenal gland problems, low blood levels of potassium or sodium, kidney problems, liver problems (eg, cirrhosis), high blood levels of chloride, or other electrolyte problems

Contact your doctor or health care provider right away if any of these apply to you.

Before using Acetazolamide Sustained-Release Capsules:

Some medical conditions may interact with Acetazolamide Sustained-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney stones, a lung disease, glaucoma (eg, chronic non-congestive angle-closure glaucoma), diabetes, or difficulty breathing
  • if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide

Some MEDICINES MAY INTERACT with Acetazolamide Sustained-Release Capsules. Tell your health care provider if you are taking any of the following medicines:

  • Salicylates (eg, aspirin) because the risk of toxic side effects of Acetazolamide Sustained-Release Capsules may be increased
  • Other carbonic anhydrase inhibitors (eg, methazolamide), cyclosporine, quinidine, phenytoin, amphetamine, or sodium bicarbonate because the actions and side effects of these medicines may be increased
  • Primidone, salicylates (eg, aspirin), lithium, or methenamine because the effectiveness of these medicines may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetazolamide Sustained-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Acetazolamide Sustained-Release Capsules:

Use Acetazolamide Sustained-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Acetazolamide Sustained-Release Capsules may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Drink plenty of water or fluids while taking Acetazolamide Sustained-Release Capsules.
  • Swallow Acetazolamide Sustained-Release Capsules whole. Do not break, crush, or chew before swallowing.
  • When you first start taking Acetazolamide Sustained-Release Capsules it may cause an increase in urine or in frequency of urination. To prevent this from affecting sleep, try not to take any dose later than 6 pm.
  • If you miss a dose of Acetazolamide Sustained-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetazolamide Sustained-Release Capsules.

Important safety information:

  • Acetazolamide Sustained-Release Capsules may cause drowsiness or temporary vision changes. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Acetazolamide Sustained-Release Capsules. Using Acetazolamide Sustained-Release Capsules alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Acetazolamide Sustained-Release Capsules may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to Acetazolamide Sustained-Release Capsules. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
  • Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Acetazolamide Sustained-Release Capsules.
  • Diabetes patients - Acetazolamide Sustained-Release Capsules may affect your blood sugar. Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • Acetazolamide Sustained-Release Capsules may interfere with certain lab tests. Make sure your doctor and laboratory personnel know you are taking Acetazolamide Sustained-Release Capsules.
  • LAB TESTS, including blood electrolyte levels, complete blood cell count, or platelet levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Acetazolamide Sustained-Release Capsules with caution in the ELDERLY because they may be more sensitive to its effects.
  • Use Acetazolamide Sustained-Release Capsules with extreme caution in CHILDREN younger than 12 years of age; safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Acetazolamide Sustained-Release Capsules during pregnancy. Acetazolamide Sustained-Release Capsules is excreted in breast milk. Do not breast-feed while taking Acetazolamide Sustained-Release Capsules.

Possible side effects of Acetazolamide Sustained-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; changes in taste; constipation; diarrhea; drowsiness; frequent urination; loss of appetite; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; changes in hearing; convulsions; dark, bloody stools; dark urine; fast breathing; fever; lack of energy; lower back pain; red, swollen, or blistered skin; ringing in the ears; sore throat; tingling of the arms or legs; unusual bleeding or bruising; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include abnormal skin sensations (eg, tingling, tickling, itching, burning); buzzing, ringing, or whistling in the ears; drowsiness; loss of appetite; loss of coordination; nausea; tremors; unsteady movements; vomiting.

Proper storage of Acetazolamide Sustained-Release Capsules:

Store Acetazolamide Sustained-Release Capsules at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetazolamide Sustained-Release Capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Acetazolamide Sustained-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Acetazolamide Sustained-Release Capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is summary only. It does not contain all information about Acetazolamide Sustained-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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