20 . April , 2018 - Friday
Check todays hot topics or new products

Find a Drug: Advanced

Please Sign in or Register

All about: Botox Parenteral-Local

Big Image

Some commonly used brand names are:

In the U.S.—

  • Botox

In Canada—

  • Botox

Category

  • Neuromuscular blocking agent

Description

Botulinum toxin type A (BOT-yoo-lye-num) is used to treat certain eye conditions, such as:

  • Blepharospasm—A condition in which the eyelid will not stay open, because of a spasm of a muscle of the eye.
  • Strabismus—A condition in which the eyes do not line up properly.

Botulinum toxin type A is injected into the surrounding muscle or tissue of the eye, but not into the eye itself. Depending on your condition, more than one treatment may be required.

Botulinum toxin type A is also used to treat muscle spasms of the neck (cervical dystonia) and some types of severe sweating of the armpits (hyperhidrosis).

This medicine is to be administered only by, or under the immediate supervision of, your doctor. It is available in the following dosage form:

  • Parenteral-Local
  • Injection (U.S. and Canada)

Before Receiving This Medicine

In deciding to receive a medicine, the risks of receiving the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For botulinum toxin type A, the following should be considered:

Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to botulinum toxin type A. Also tell your health care professional if you are allergic to any other substances.

Pregnancy—Studies on effects in pregnancy have not been done in either humans or animals. Tell your doctor if you are pregnant or if you plan to become pregnant while using this medication.

Breast-feeding—It is not known whether botulinum toxin type A passes into the breast milk. Tell your doctor if you are breast feeding.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of botulinum toxin type A in children with use in other age groups.

Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Elderly people are especially sensitive to the effects of some medicines. This may increase the chance of side effects during treatment.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are using any other ophthalmic prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems—The presence of other medical problems may affect the use of botulinum toxin type A. Make sure you tell your doctor if you have any other medical problems, especially:

  • Amyotrophic lateral sclerosis (Lou Gehrig's disease) or
  • Lambert-Eaton syndrome or
  • Motor neuropathy or
  • Myasthenia gravis—These medical problems may increase your risk for severe swallowing or breathing problems.
  • Heart problems or other medical conditions that may worsen with rapidly increasing activity—Treatment with botulinum toxin type A may give you better vision and the desire to become more active in your daily life; this may put a strain on your heart and body
  • Infection where botulinum toxin type A is to be injected—Botulinum toxin type A should not injected into an area that is infected.
  • Infection with Clostridium botulinum toxin (botulism poisoning), history of—Persons with a history of infection with Clostridium botulinum toxin (botulism poisoning) may have produced antibodies that may interfere with botulinum toxin type A therapy and make it less effective
  • Nerve problems—May increase your chance of getting side effects.
  • Swallowing problems—Treatment with botulinum toxin type A may make this problem worse and increase your risk for serious side effects. Tell your doctor right away if you have severe swallowing problems.
  • Swelling where botulinum toxin type A is to be injected or
  • Weakness in the muscles where botulinum toxin type A is to be injected—Your doctor may decrease your dose or not inject the botulinum toxin type A until these problems are better.

Proper Use of This Medicine

Dosing—The dose of botulinum toxin type A will be different for different patients. The following information includes only the average doses of botulinum toxin type A.

  • For injection dosage form:
    • For certain eye conditions:
      • Adults and children 12 years of age and older—One or more injections into the muscles around the eyes one or more times, depending on the condition being treated.
      • Children up to 12 years of age—Use and dose must be determined by your doctor.
    • For muscle spasms of the neck (cervical dystonia):
      • Adults and children 16 years of age and older—One or more injections into the muscles of the neck one or more times, depending on the condition being treated.
      • Children up to 16 years of age—Use and dose must be determined by your doctor.
    • For severe sweating of the armpits (hyperhidrosis):
      • Adults and children 16 years of age and older—One or more injections just below the skin in the armpit one or more times.
      • Children up to 16 years of age—Use and dose must be determined by your doctor.

Precautions After Receiving This Medicine

After you have received this medicine and your vision is better, you may find that you are a lot more active than you were before. You should increase your activities slowly and carefully to allow your heart and body time to get stronger. Also, before you start any exercise program, check with your doctor.

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur :

More common—For blepharospasm

Dryness of the eye; inability to close the eyelid completely

Less common or rare—For blepharospasm

Decreased blinking; irritation of the cornea (colored portion) of the eye; turning outward or inward of the edge of the eyelid

Other side effects may occur that usually do not need medical attention. These side effects may go away as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common—For blepharospasm

Blue or purplish bruise on eyelid; drooping of the upper eyelid; irritation or watering of the eye; sensitivity of the eye to light

More common—For cervical dystonia

Body aches or pain; chills; cough, fever, sneezing, or sore throat; difficulty in breathing; difficulty swallowing; ear congestion; headache; loss of voice; nasal congestion; neck pain; runny nose; unusual tiredness or weakness

More common—For horizontal strabismus

Drooping of the upper eyelid; eye pointing upward or downward instead of straight ahead

More common—For hyperhidrosis

Back, neck, or side pain; body aches or pain; chills; congestion; cough; diarrhea; dryness or soreness of throat; fear; fever; general feeling of discomfort or illness; headache; heavy bleeding from place where shot was given; hoarseness; itching skin; joint pain; loss of appetite; muscle aches and pains; nausea; nervousness; painful or difficult urination; runny nose; shivering; sore throat; sweating; tender, swollen glands in neck; trouble sleeping; trouble in swallowing; unusual tiredness or weakness; voice changes; vomiting

Less common or rare—For blepharospasm or strabismus

Skin rash; swelling of the eyelid skin

Less common or rare—For horizontal strabismus

Difficulty finding the location of objects; double vision

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Additional Information

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, botulinum toxin type A is used in certain patients with the following medical conditions:

  • Deep facial lines or wrinkles
  • Frey's syndrome (gustatory sweating) (red area and sweating on the cheek while eating)
  • Hyperhidrosis (severe sweating of the palms)
  • Spasms of the arms, feet, hands, or legs caused by brain injury, multiple sclerosis, spinal cord injury, or stroke
  • Spasms of the arms and legs in stroke patients
  • Spasms of the face
  • Spasms of the hand, including writer's cramp and musician's cramp
  • Spasms of the arms and legs in patients with multiple sclerosis
  • Spasms of the vocal cords

Revised: 02/23/2006

The information contained in the Thomson Healthcare (Micromedex) products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Healthcare does not assume any responsibility or risk for your use of the Thomson Healthcare products.

Recent Drug Updates at DrugIndexOnline:





Carbinoxamine Maleate Liquid Carbinoxamine Maleate Liquid
Generic Name: Carbinoxamine Maleate Liquid (kar-bi-NOX-a-meen) Brand Name: Examples include Histex Pd and PediatexCarbinoxamine Maleate Liquid is used for:Treating allergy symptoms such as runny nose, watery/itchy eyes, rash, or hives. It may also be used for other conditions as determined by y more...

Doral Doral
Generic name: Quazepam Brand names: Doral Why is Doral prescribed? Doral, a sleeping medication available in tablet form, is taken as short-term treatment for insomnia. Symptoms of insomnia may include difficulty falling asleep, frequent awakenings throughout the night, or very early morning awa more...

Enduronyl Enduronyl
Generic Name: methyclothiazide and deserpidine Dosage Form: Tablets WARNING:This fixed combination drug is not indicated for initial therapy of hypertension. Hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use more...

Genebs Regular Strength Tablets Genebs Regular Strength Tablets
Some commonly used brand names are: In the U.S.— Aceta Elixir 1 Aceta Tablets 1 Acetaminophen Uniserts 1 Actamin 1 Actamin Extra 1 Actamin Super 2 Aminofen 1 Aminofen Max 1 Apacet Capsules 1 Apacet Elixir 1 Apacet Extra Strength Caplets 1 Apacet Extra Strength Tablets 1 Apacet, Infants' 1 more...

Gentamicin Drops Gentamicin Drops
Generic Name: Gentamicin Eye Drops (jen-ta-MYE-sin) Brand Name: Examples include Genoptic and GentakGentamicin Drops is used for:Treating surface eye infections caused by certain bacteria. It may also be used for other conditions as determined by your doctor. Gentamicin Drops is a topical antib more...

Isotretinoin (13-cis-Retinoic Acid) Isotretinoin (13-cis-Retinoic Acid)
( 13-cis-Retinoic Acid ) Pronouncation: (EYE-so-TREH-tih-NO-in) Class: First generation retinoid Trade Names: Accutane - Capsules 10 mg - Capsules 20 mg - Capsules 40 mg Trade Names: Claravis - Capsules 10 mg - Capsules 20 mg - Capsules 40 mg Accutane Roche (Canada) Isotrex (Canada) Mechanism of Ac more...

Klor-Con Klor-Con
Generic name: Potassium chloride Brand names: Slow-K, Kaon-CL, K-Dur, K-Tab, Klor-Con, Micro-K Why is Klor-Con prescribed? Micro-K is used to treat or prevent low potassium levels in people who may face potassium loss caused by digitalis (Lanoxin), non-potassium-sparing diuretics (such as Diuril more...

Meperidine injection Meperidine injection
Generic Name: Meperidine Hydrochloride Dosage Form: Injection Meperidine Description Meperidine Hydrochloride Injection, USP 10 mg/mL is a sterile, non pyrogenic, hypotonic solution of Meperidine hydrochloride in Water for Injection. This product is to be administered by the intravenous ro more...