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All about: Choriogonadotropin Alfa

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Generic Name: Choriogonadotropin Alfa (kor-ee-OH-goe-NAD-oh-troe-pin)
Brand Name: Ovidrel

Choriogonadotropin Alfa is used for:

Treating infertility in certain women who have not gone through menopause.

Choriogonadotropin Alfa is a hormone. Human chorionic gonadotropin (HCG) helps to produce mature eggs in women undergoing fertility procedures such as in vitro fertilization and it also stimulates ovulation (release of an egg). It may also be used for other conditions as determined by your doctor.

Do NOT use Choriogonadotropin Alfa if:

  • you are allergic to any ingredient in Choriogonadotropin Alfa
  • you have abnormal bleeding of the uterus of unknown cause, brain lesion or tumor (eg, pituitary gland tumor), primary ovarian failure, enlarged ovary or ovarian cyst of unknown cause, uncontrolled thyroid or adrenal gland problems, or tumors in the reproductive tract or liver that are sex hormone dependent
  • if you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Choriogonadotropin Alfa :

Some medical conditions may interact with Choriogonadotropin Alfa . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are planning to become pregnant or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have adrenal gland disease, bleeding in the reproductive or urinary tract, or thyroid disease

Some MEDICINES MAY INTERACT with Choriogonadotropin Alfa . However, no specific interactions with Choriogonadotropin Alfa are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Choriogonadotropin Alfa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Choriogonadotropin Alfa :

Use Choriogonadotropin Alfa as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Choriogonadotropin Alfa is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using Choriogonadotropin Alfa at home, carefully follow the injection procedures taught to you by your health care provider.
  • Choriogonadotropin Alfa comes in a single-use syringe. It is given as an injection under the skin. Wash your hands with soap and water before you begin. Wipe the appropriate injection site with an alcohol swab. Remove the cap from the needle of the syringe. Do not touch the needle or allow the needle to touch anything else. Use the technique you have been shown to give the injection. After giving the injection, cover the injection site with a small bandage if necessary. Discard all used material appropriately.
  • If Choriogonadotropin Alfa contains particles or is discolored, or if it is cracked or damaged in any way, do not use it.
  • Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Choriogonadotropin Alfa , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Choriogonadotropin Alfa .

Important safety information:

  • Choriogonadotropin Alfa may cause dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Choriogonadotropin Alfa . Using Choriogonadotropin Alfa alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
  • You must receive a thorough gynecological exam before beginning treatment with Choriogonadotropin Alfa .
  • Use of Choriogonadotropin Alfa can increase your risk of multiple births (eg, twins or triplets), blood clots, enlarged ovaries, and ruptured ovarian cysts. Discuss this risk with your doctor.
  • LAB TESTS, including blood hormone levels and ultrasound exams, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: Do not use Choriogonadotropin Alfa if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is unknown if Choriogonadotropin Alfa is excreted in breast milk. If you are or will be breast-feeding while you are using Choriogonadotropin Alfa , check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Choriogonadotropin Alfa :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nausea; pain, swelling, bruising, or redness at the injection site; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloating or swelling in the stomach or pelvic area; breast pain; chest pain; infrequent urination; irregular heartbeat; leg pain; persistent or severe nausea, vomiting, or diarrhea; severe pelvic pain; stomach pain; sudden shortness of breath; weight gain.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Choriogonadotropin Alfa :

Choriogonadotropin Alfa is usually handled and stored by a health care provider. If you are using Choriogonadotropin Alfa at home, store Choriogonadotropin Alfa as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Choriogonadotropin Alfa out of the reach of children and away from pets.

General information:

  • If you have any questions about Choriogonadotropin Alfa , please talk with your doctor, pharmacist, or other health care provider.
  • Choriogonadotropin Alfa is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Choriogonadotropin Alfa . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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