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All about: citric acid and sodium citrate

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Generic Name: citric acid and sodium citrate (sit trick acid and sew dee umm sit trayt)
Brand Names: Bicitra, Cytra-2, Oracit

What is citric acid and sodium citrate?

Citric acid and sodium citrate are alkalinizing agents that make the urine less acidic.

Citric acid and sodium citrate is used in the treatment of certain kidney disorders, including kidney stones, and for gout.

Citric acid and sodium citrate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about citric acid and sodium citrate?

Take citric acid and sodium citrate exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Take citric acid and sodium citrate with food or a snack.

What should I discuss with my health care provider before taking citric acid and sodium citrate?

Before taking citric acid and sodium citrate, tell your doctor if you have:

  • kidney disease;

  • high blood pressure or a restricted sodium diet;

  • Addison's disease,

  • liver disease; or

  • edema or swelling of the legs or ankles;

  • lung disease; or

  • heart disease.

It is not known whether citric acid and sodium citrate will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known if citric acid and sodium citrate passes into breast milk. Do not take citric acid and sodium citrate without first talking to your doctor if you are breast-feeding a baby.

How should I take citric acid and sodium citrate?

Take citric acid and sodium citrate exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Dilute citric acid and sodium citrate in 6 ounces of water before drinking to help prevent an upset stomach. Drink another glass of water after taking the medication.

Take each dose with a full glass of water. Take citric acid and sodium citrate with food or a snack.

Citric acid and sodium citrate can be chilled in order to better the taste, however, do not freeze the medication.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next dose however, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a citric acid and sodium citrate overdose may include diarrhea, nausea, vomiting, and seizures.

What should I avoid while taking citric acid and sodium citrate?

Citric acid and sodium citrate contains sodium. If you are on a sodium restricted diet or have high blood pressure talk to your health care professional before taking citric acid and sodium citrate.

Citric acid and sodium citrate side effects

If you experience any of the following serious side effects, stop taking citric acid and sodium citrate and contact your doctor immediately or seek emergency medical treatment:
  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives);

  • wheezing or shortness of breath;

  • an unusually slow or irregular heartbeat;

  • swelling of the feet and lower legs;

  • leg pain or cramping;

  • sudden weight gain (more than 2 pounds in one day or 5 pounds in one week);

  • chest (heart) pain;

  • tremor or muscle twitching

  • severe diarrhea or stomach pain

If you experience any of the following less serious side effects, continue taking citric acid and sodium citrate and talk to your doctor:

  • stomach ache;

  • diarrhea, constipation, gas; or

  • nausea, or vomiting.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect citric acid and sodium citrate?

Before taking citric acid and sodium citrate, tell your doctor if you are taking:

  • ammonium chloride;

  • quinidine;

  • amphetamine and dextroamphetamine (Adderall);

  • antacids (especially those containing aluminum hydroxide or calcium carbonate);

  • aspirin or aspirin-like drugs used for pain relief (salicylates, NSAIDs (e.g., ibuprofen, naproxen))

  • methenamine;

  • antibiotics (ciprofloxacin, norfloxacin, ofloxacin);

  • ephedrine or pseudoephedrine;

  • tetracycline;

  • heart medicines;

  • anole antifungal (e.g., ketoconazole, itraconazole);

  • chlorpropamide;

  • diet medicines; or

  • lithium (Lithobid).

You may not be able to take citric acid and sodium citrate, or you may require a dosage adjustment or special monitoring during treatment.

Drugs other than those listed here may also interact with citric acid and sodium citrate or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

  • Your pharmacist has additional information about citric acid and sodium citrate written for health professionals that your may read.

What does my medication look like?

Citric acid and sodium citrate is available with a prescription under the brand names Bicitra, Oracit, and Cytra-2. Other brand or generic formulations of this medication may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2006 Cerner Multum, Inc. Version: 1.01. Revision Date: 7/13/05 5:03:48 PM.

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