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All about: Clotrimazole Inserts

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Generic Name: Clotrimazole Vaginal Inserts (3 Day) (kloe-TRIM-a-zole)
Brand Name: Gyne-Lotrimin

Clotrimazole Inserts is used for:

Treating vaginal yeast infections.

Clotrimazole Inserts is an antifungal agent. It works by weakening the cell membrane of the fungus, resulting in the death of the fungus.

Do NOT use Clotrimazole Inserts if:

  • you are allergic to any ingredient in Clotrimazole Inserts
  • you have never had a vaginal yeast infection diagnosed by a doctor
  • you have itching caused by a condition other than a yeast infection
  • you have stomach, shoulder, or lower back pain; fever; chills; nausea; foul-smelling vaginal discharge; or vomiting

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clotrimazole Inserts:

Some medical conditions may interact with Clotrimazole Inserts. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have the blood disease porphyria or a history of liver disease or diabetes, or you have been exposed to HIV
  • if this is the first time you have had vaginal itching and discomfort
  • if you have vaginal yeast infections often (eg, your symptoms return within 2 months) or your symptoms do not clear up with treatment
  • if you are taking antibiotics

Some MEDICINES MAY INTERACT with Clotrimazole Inserts. However, no specific interactions with Clotrimazole Inserts are known at this time.

Ask your health care provider if Clotrimazole Inserts may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clotrimazole Inserts:

Use Clotrimazole Inserts as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Clotrimazole Inserts. Talk to your pharmacist if you have questions about this information.
  • Clotrimazole Inserts is for vaginal use only. Do not use it rectally or take by mouth.
  • Using the applicator provided, insert 1 suppository high into the vagina at bedtime for 3 days.
  • Some forms of this product come with 3 disposable applicators. If this product contains disposable applicators, throw away each applicator after use.
  • Some forms of this product come with one applicator to be used for all 3 days of treatment. If this product contains only one applicator, do not throw it away after use. Separate the pieces of the applicator and wash with warm, soapy water immediately after use. Rinse thoroughly. Make sure the applicator is completely dry before the next use.
  • Wash your hands immediately after using Clotrimazole Inserts.
  • To clear up your infection completely, use Clotrimazole Inserts for the full course of treatment. Keep using it even if you feel better in a few days.
  • If you miss a dose of Clotrimazole Inserts, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Clotrimazole Inserts.

Important safety information:

  • Clotrimazole Inserts is for vaginal use only. Avoid contact with the eyes, nose, or mouth. If you get Clotrimazole Inserts in your eyes, flush with a generous amount of cool water.
  • Be sure to use Clotrimazole Inserts for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • If your symptoms do not improve within 3 days, if they last more than 7 days, or if they get worse, check with your doctor.
  • Do not use Clotrimazole Inserts for itching caused by other conditions.
  • Dry the outside vaginal area completely after showering, bathing, or swimming. Do not go swimming for at least 9 to 12 hours after applying Clotrimazole Inserts. Change out of wet bathing suits or damp workout clothes as soon as possible.
  • Continue using Clotrimazole Inserts even during your menstrual period. Do not use tampons while you are using Clotrimazole Inserts or until all of your symptoms go away. Use unscented pads or pantiliners.
  • Do not have vaginal sexual intercourse while you are using Clotrimazole Inserts.
  • Clotrimazole Inserts may decrease the effectiveness of condoms and diaphragms, increasing the chance of pregnancy or risk of sexually transmitted disease.
  • Do not use tampons, douches, spermicides, or other vaginal products while using Clotrimazole Inserts.
  • or if they get worse, check with your doctor.
  • Clotrimazole Inserts should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Clotrimazole Inserts while you are pregnant. It is not known if Clotrimazole Inserts is found in breast milk. If you are or will be breast-feeding while you use Clotrimazole Inserts, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Clotrimazole Inserts:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Mild vaginal burning, irritation, or itching.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever or chills; foul-smelling vaginal discharge; nausea; severe or prolonged vaginal burning, irritation, or itching; stomach pain; swelling; vomiting.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Clotrimazole Inserts:

Store Clotrimazole Inserts at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Avoid temperatures above 86 degrees F (30 degrees C). Avoid freezing. Do not store in the bathroom. Do not use if the wrapper on the applicator or suppository is torn or damaged. Keep Clotrimazole Inserts out of the reach of children and away from pets.

General information:

  • If you have any questions about Clotrimazole Inserts, please talk with your doctor, pharmacist, or other health care provider.
  • Clotrimazole Inserts is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Clotrimazole Inserts. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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