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All about: Cyanocobalamin (B12) Gel

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Generic Name: Cyanocobalamin (B12) Nasal Gel (sigh-an-oh-koe-BAL-uh-min)
Brand Name: Nascobal

Cyanocobalamin (B12) Gel is used for:

Maintaining normal vitamin B12 blood levels in certain patients with pernicious anemia. It is also used to treat or prevent low blood levels of vitamin B12 that may be caused by other conditions.

Cyanocobalamin (B12) Gel is a form of vitamin B12. It works by replacing vitamin B12 in the body.

Do NOT use Cyanocobalamin (B12) Gel if:

  • you are allergic to any ingredient in Cyanocobalamin (B12) Gel, including cobalt

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cyanocobalamin (B12) Gel:

Some medical conditions may interact with Cyanocobalamin (B12) Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a stuffy nose, allergies, or upper respiratory tract infection
  • if you have an infection, Leber disease (weakened eye nerve), a buildup of waste in the blood (uremia), any kind of anemia, or low blood levels of iron or folic acid
  • if you are a vegetarian
  • if you drink alcohol on a regular basis

Some MEDICINES MAY INTERACT with Cyanocobalamin (B12) Gel. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Chloramphenicol or other medicine that may decrease your bone marrow because effectiveness of Cyanocobalamin (B12) Gel may be decreased; ask your doctor if you are unsure if any of your medicines may decrease your bone marrow
  • Colchicine or para-aminosalicylic acid because the effectiveness of Cyanocobalamin (B12) Gel may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cyanocobalamin (B12) Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cyanocobalamin (B12) Gel:

Use Cyanocobalamin (B12) Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Cyanocobalamin (B12) Gel comes with an additional patient leaflet. Read it carefully and reread it each time you get Cyanocobalamin (B12) Gel refilled.
  • Follow the directions provided by your doctor, pharmacist, or other health care provider regarding how to use Cyanocobalamin (B12) Gel. If you are unsure how to use Cyanocobalamin (B12) Gel, contact your doctor or other health care provider.
  • Cyanocobalamin (B12) Gel is used in the nose.
  • Do not use Cyanocobalamin (B12) Gel within 1 hour before or after eating or drinking hot foods or liquids.
  • If you miss a dose of Cyanocobalamin (B12) Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Cyanocobalamin (B12) Gel.

Important safety information:

  • Heavy alcohol intake for more than 2 weeks may decrease the effectiveness of Cyanocobalamin (B12) Gel. Check with your doctor if you drink alcohol on a regular basis.
  • Do not substitute folic acid for Cyanocobalamin (B12) Gel without first checking with your doctor. Folic acid may prevent anemia but may not prevent other serious symptoms such as spinal cord problems.
  • You should have blood tests every 3 to 6 months to monitor your progress.
  • Certain medicines, including antibiotics, methotrexate, or pyrimethamine, may interfere with lab tests for vitamin B12 and folic acid. Be sure your doctor and lab personnel know all the medicines that you are taking.
  • Do not take large doses of vitamins (megadoses or megavitamin therapy) while taking Cyanocobalamin (B12) Gel unless directed by your doctor.
  • LAB TESTS, including complete blood cell counts, platelet counts, and blood potassium, vitamin B12, and folic acid levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Cyanocobalamin (B12) Gel, discuss with your doctor the benefits and risks of using Cyanocobalamin (B12) Gel during pregnancy. Cyanocobalamin (B12) Gel is excreted in breast milk. If you are or will be breast-feeding while you are using Cyanocobalamin (B12) Gel, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Cyanocobalamin (B12) Gel:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fever, chills, or persistent sore throat; irregular heartbeat; muscle weakness or cramping; shortness of breath; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately.

Proper storage of Cyanocobalamin (B12) Gel:

Store Cyanocobalamin (B12) Gel at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Store upright. Do not freeze. Do not store in the bathroom. Keep Cyanocobalamin (B12) Gel out of the reach of children and away from pets.

General information:

  • If you have any questions about Cyanocobalamin (B12) Gel, please talk with your doctor, pharmacist, or other health care provider.
  • Cyanocobalamin (B12) Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Cyanocobalamin (B12) Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 5, 2007
Database Edition 07.3.1.003
Copyright © 2007 Wolters Kluwer Health, Inc.

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