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All about: Cyclosporine

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Generic name: Cyclosporine
Brand names: Restasis

Why is Cyclosporine prescribed?

Restasis is a medicated eye drop that increases tear production. It is used to relieve the symptoms of dry eye syndrome, including burning, redness, dryness, grittiness, and the sensation of a foreign object stuck in the eye.

Most important fact about Cyclosporine

Do not use Restasis to treat eye dryness that is related to an infection.

How should you take Cyclosporine?

Use Restasis solution only in the eyes; never swallow it. Turn each individual, single-use vial upside down a few times before using to mix the solution (it should look white with no streaks). After opening the vial, immediately insert the drops into one or both eyes; throw away any remaining medication when you're done.

To prevent contamination of the solution, do not touch the tip of the vial to any surface, to your eyelids, or to the surrounding area of the eye.

If you wear contact lenses, wait at least 15 minutes after using Restasis before inserting your lenses. This will prevent them from absorbing the medication. It's okay to use lubricating eye drops or artificial tears during treatment with Restasis, but you should wait 15 minutes after using one product before using the other one.

--If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take two doses at once.

--Storage instructions...

Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe to continue using Restasis.

  • More common side effects may include:
    Burning in the eye

Why should Cyclosporine not be prescribed?

Do not use Restasis if you currently have an eye infection. Also avoid the drug if you've ever had an allergic reaction to it.

Special warnings about Cyclosporine

Be sure to tell the doctor if you've ever had herpes in either eye. Restasis has not been studied in people who have a history of eye-related herpes infection.

If you wear contact lenses, talk to your doctor before using Restasis. People with reduced tear production generally should not wear contact lenses.

Restasis has not been studied in children less than 16 years old.

Possible food and drug interactions when taking Cyclosporine

No interactions with Restasis have been reported.

Special information if you are pregnant or breastfeeding

Restasis has not been adequately studied in pregnant women. Before using the drug, let your doctor know if you are pregnant or plan to become pregnant.

It is not known whether Restasis appears in breast milk. If you plan to breastfeed, discuss your medication options with your doctor.

Recommended dosage

The usual dose is one drop in each affected eye twice a day, about 12 hours apart.


There is no information on Restasis overdose. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

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