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All about: Dianeal with Dextrose

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Generic Name: Sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose
Dosage Form: Injection, solution

Dianeal with Dextrose Description

DIANEAL Low Calcium peritoneal dialysis solutions are sterile, nonpyrogenic solutions in AMBU-FLEX III containers with flanged port for intraperitoneal administration only. They contain no bacteriostatic or antimicrobial agents or added buffers.

Composition, calculated osmolarity, pH and ionic concentrations are shown in Table 1.

Potassium is omitted from peritoneal dialysis solutions because dialysis may be performed to correct hyperkalemia. In situations in which there is a normal serum potassium level or hypokalemia, the addition of potassium chloride (up to a concentration of 4 mEq/L) may be indicated to prevent severe hypokalemia. Addition of potassium chloride should be made after careful evaluation of serum and total body potassium and only under the direction of a physician. Frequent monitoring of serum electrolytes is indicated.

In some patients calcium carbonate is used as a phosphate binder. Because serum calcium levels have been observed to be elevated in these patients (Slatopolsky et al. 1986), the calcium concentration of DIANEAL Low Calcium peritoneal dialysis solutions has been reduced to 2.5 mEq/L. Serum calcium levels should be monitored and if low, the amount of oral calcium carbonate phosphate binder may be increased or peritoneal dialysis solutions containing higher calcium concentrations may be used. If serum calcium levels rise, adjustments to the dosage of the calcium carbonate phosphate binder and/or vitamin D analogs should be considered by the physician.

Because average plasma magnesium levels in some chronic CAPD patients have been observed to be elevated (Nolph et al. 1981), the magnesium concentration of this formulation has been reduced to 0.5 mEq/L. Average plasma magnesium levels have not been reported for chronic IPD and CCPD patients. Serum magnesium levels should be monitored and if low, oral magnesium supplements, oral magnesium containing phosphate binders, or peritoneal dialysis solutions containing higher magnesium concentrations may be used.

Because average serum bicarbonate levels in some chronic CAPD patients (Nolph et al. 1981), some chronic IPD patients (La Greca et al. 1980), and some chronic CCPD patients (Diaz-Buxo et al. 1983), have been observed to be somewhat lower than normal values, the bicarbonate precursor (lactate) concentration of DIANEAL Low Calcium peritoneal dialysis solutions has been raised to 40 mEq/L. Serum bicarbonate levels should be monitored.

The osmolarities shown in Table 1 are calculated values. Calculated osmolarity of DIANEAL Low Calcium peritoneal dialysis solution with 1.5% dextrose is 344 mOsmol/L, compared with measured values in normal human serum of 280 mOsmol/L.

The plastic container is fabricated from a specially formulated polyvinyl chloride (PL 146 Plastic). The amount of water that can permeate from inside the container into the overpouch is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million; however, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.

Dianeal with Dextrose - Clinical Pharmacology

Peritoneal dialysis is a procedure for removing toxic substances and metabolites normally excreted by the kidneys, and for aiding in the regulation of fluid and electrolyte balance.

The procedure is accomplished by instilling peritoneal dialysis fluid through a conduit into the peritoneal cavity. With the exception of lactate, present as a bicarbonate precursor, electrolyte concentrations in the fluid have been formulated in an attempt to normalize plasma electrolyte concentrations resulting from osmosis and diffusion across the peritoneal membrane (between the patient’s plasma and the dialysis fluid). Toxic substances and metabolites, present in high concentrations in the blood, cross the peritoneal membrane into the dialyzing fluid. Dextrose in the dialyzing fluid is used to produce a solution hyperosmolar to the plasma, creating an osmotic gradient which facilitates fluid removal from the patient’s plasma into the peritoneal cavity. After a period of time (dwell time), the fluid is drained by gravity from the cavity.

Indications and Usage for Dianeal with Dextrose

DIANEAL Low Calcium peritoneal dialysis solutions are indicated for use in chronic renal failure patients being maintained on peritoneal dialysis.

Contraindications

None known.

Warnings

Peritoneal dialysis should be done with great care, if at all, in patients with a number of abdominal conditions including disruption of the peritoneal membrane or diaphragm by surgery or trauma, extensive adhesions, bowel distention, undiagnosed abdominal disease, abdominal wall infection, hernias or burns, fecal fistula or colostomy, tense ascites, obesity, and large polycystic kidneys (Vaamonde and Perez 1977). Other conditions include recent aortic graft replacement and severe pulmonary disease. When assessing peritoneal dialysis as the mode of therapy in such extreme situations, the benefits to the patient must be weighed against the possible complications.

An accurate fluid balance record must be kept and the weight of the patient carefully monitored to avoid over or under hydration with severe consequences including congestive heart failure, volume depletion, and shock.

Excessive use of DIANEAL Low Calcium peritoneal dialysis solution with 3.5% or 4.25% dextrose during a peritoneal dialysis treatment can result in significant removal of water from the patient.

Stable patients undergoing maintenance peritoneal dialysis should have routine periodic evaluation of blood chemistries and hematologic factors, as well as other indicators of patient status.

In some patients calcium carbonate is used as a phosphate binder. Because serum calcium levels have been observed to be elevated in these patients (Slatopolsky et al. 1986), the calcium concentration of DIANEAL Low Calcium peritoneal dialysis solutions has been reduced to 2.5 mEq/L. Serum calcium levels should be monitored and if low, the amount of oral calcium carbonate phosphate binder may be increased or peritoneal dialysis solutions containing higher calcium concentrations may be used. If serum calcium levels rise, adjustments to the dosage of the calcium carbonate phosphate binder and/or vitamin D analogs should be considered by the physician.

Because average plasma magnesium levels in some chronic CAPD patients have been observed to be elevated (Nolph et al. 1981), the magnesium concentration of this formulation has been reduced to 0.5 mEq/L. Average plasma magnesium levels have not been reported for chronic IPD and CCPD patients. Serum magnesium levels should be monitored and if low, oral magnesium supplements, oral magnesium containing phosphate binders, or peritoneal dialysis solutions containing higher magnesium concentrations may be used.

Because average serum bicarbonate levels in some chronic CAPD patients (Nolph et al. 1981), some chronic IPD patients (La Greca et al. 1980), and some chronic CCPD patients (Diaz-Buxo et al. 1983), have been observed to be somewhat lower than normal values, the bicarbonate precursor (lactate) concentration of DIANEAL Low Calcium peritoneal dialysis solutions has been raised to 40 mEq/L. Serum bicarbonate levels should be monitored.

Not for use in the treatment of lactic acidosis.

Potassium is omitted from DIANEAL Low Calcium peritoneal dialysis solutions because dialysis may be performed to correct hyperkalemia. Addition of potassium chloride should be made after careful evaluation of serum and total body potassium and only under the direction of a physician.

The use of 5 or 6 liters of dialysis solution is not indicated in a single exchange.

Do not use 6 liter product with Pac-X or Pac-Xtra hardware.

Refer to manufacturer’s directions accompanying drugs to obtain full information on additives.

If the resealable rubber plug on the medication port is missing or partially removed, do not use product if medication is to be added.

After removing overpouch, check for minute leaks by squeezing container firmly. If leaks are found, discard the solution because the sterility may be impaired.

Freezing of solution may occur at temperatures below 0°C (32°F). Allow to thaw naturally in ambient conditions and thoroughly mix contents by shaking.

Precautions

Aseptic technique must be used throughout the procedure and at its termination in order to reduce the possibility of infection. If peritonitis occurs, the choice and dosage of antibiotics should be based upon the results of identification and sensitivity studies of the isolated organism(s) when possible. Prior to identification of the involved organism(s), broad-spectrum antibiotics may be indicated.

Peritoneal dialysis solutions may be warmed in the overpouch to 37°C (98.6°F) to enhance patient comfort. However, only dry heat (for example, heating pad) should be used. Solutions should not be heated in water due to an increased risk of infection. Microwave ovens should not be used to heat solutions because there is a potential for damage to the solution container. Moreover, microwave oven heating may potentially cause overheating and/or non-uniform heating of the solution that may result in patient injury or discomfort.

Significant losses of protein, amino acids and water soluble vitamins may occur during peritoneal dialysis. Replacement therapy should be provided as necessary.

Pregnancy

Teratogenic Effects

Pregnancy Category C

Animal reproduction studies have not been conducted with DIANEAL Low Calcium peritoneal dialysis solutions. It is also not known whether DIANEAL Low Calcium peritoneal dialysis solutions can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. DIANEAL Low Calcium peritoneal dialysis solutions should be given to a pregnant woman only if clearly needed.

Do not administer unless solution is clear and seal is intact.

Adverse Reactions

Adverse reactions to peritoneal dialysis include mechanical and solution related problems as well as the results of contamination of equipment or improper technique in catheter placement. Abdominal pain, bleeding, peritonitis, subcutaneous infection around a chronic peritoneal catheter, catheter blockage, difficulty in fluid removal, and ileus are among the complications of the procedure. Solution related adverse reactions may include electrolyte and fluid imbalances, hypovolemia, hypervolemia, hypertension, hypotension, disequilibrium syndrome, and muscle cramping.

When prescribing the solution to be used for an individual patient, consideration should be given to the potential interaction between the dialysis treatment and therapy directed at other existing illnesses. For example, rapid potassium removal may create arrhythmias in cardiac patients using digitalis or similar drugs; digitalis toxicity may be masked by elevated potassium or magnesium, or by hypocalcemia. Correction of electrolytes by dialysis may precipitate signs and symptoms of digitalis excess. Conversely, toxicity may occur at suboptimal dosages of digitalis if potassium is low or calcium high. Azotemic diabetics require careful monitoring of insulin requirements during and following dialysis with dextrose containing solutions.

Dianeal with Dextrose Dosage and Administration

DIANEAL Low Calcium peritoneal dialysis solutions are intended for intraperitoneal administration only.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

The mode of therapy (Intermittent Peritoneal Dialysis [IPD], Continuous Ambulatory Peritoneal Dialysis [CAPD], or Continuous Cyclic Peritoneal Dialysis [CCPD]), frequency of treatment, formulation, exchange volume, duration of dwell, and length of dialysis should be selected by the physicianresponsible for and supervising the treatment of the individual patient.

To avoid the risk of severe dehydration and hypovolemia and to minimize the loss of protein, it is advisable to select the peritoneal dialysis solution with the lowest level of osmolarity consistent with the fluid removal requirements for that exchange.

Peritoneal dialysis solutions may be warmed in the overpouch to 37°C (98.6°F) to enhance patient comfort. However, only dry heat (for example, heating pad) should be used. (See Directions for Use)

The addition of heparin to the dialysis solution may be indicated to aid in prevention of catheter blockage in patients with peritonitis, or when the solution drainage contains fibrinous or proteinaceous material (Ribot et al. 1966). 1000 to 2000 USP units of heparin per liter of solution has been recommended for adults (Furman et al. 1978). For children, 50 units of heparin per 100 mL of dialysis fluid has been recommended (Irwin et al. 1981).

Additives may be incompatible. Complete information is not available. Those additives known to be incompatible should not be used. Consult with pharmacist, if available. If, in the informed judgment of the physician, it is deemed advisable to introduce additives, use aseptic technique. Mix thoroughly when additives have been introduced. Do not store solutions containing additives.

Intermittent Peritoneal Dialysis (IPD)

For maintenance dialysis of chronic renal failure patients.

The cycle of instillation, dwell and removal of dialysis fluid is repeated sequentially over a period of hours (8 to 36 hours) as many times per week as indicated by the condition of the patient. For chronic renal failure patients, maintenance dialysis is often accomplished by periodic dialysis (3 to 5 times weekly) for shorter time periods (8 to 14 hours per session) (Mattocks and El-Bassiouni 1971).

Continuous Ambulatory Peritoneal Dialysis (CAPD) and Continuous Cyclic Peritoneal Dialysis (CCPD)

For maintenance dialysis of chronic renal failure patients.

In CAPD, typically 1.5 to 3.0 liters of dialysis solution (depending upon patient size) are instilled into the peritoneal cavity of adults and the peritoneal access device is then clamped (Kim et al. 1984; Twardowski and Janicka 1981; Twardowski and Burrows 1984). For children, 30 to 50 mL/kg body weight with a maximum of 2 liters has been recommended (Potter et al. 1981; Irwin et al. 1981). The solution remains in the cavity for dwell times of 4 to 8 hours during the day and 8 to 12 hours overnight. At the conclusion of each dwell period, the access device is opened, the solution drained and fresh solution instilled. The procedure is repeated 3 to 5 times per day, 6 to 7 days per week. Solution exchange volumes and frequency of exchanges should be individualized for adequate biochemical and fluid volume control (Moncrief et al. 1982; Twardowski et al. 1983). The majority of exchanges will utilize 1.5% or 2.5% dextrose containing peritoneal dialysis solutions, with 3.5% or 4.25% dextrose containing solutions being used when extra fluid removal is required. Patient weight is used as the indicator of the need for fluid removal (Popovich et al. 1978).

In CCPD, the patient receives 3 or 4 dialysis exchanges during the night which range from 2-1/2 to 3 hours dwell duration. Typically 1.5 to 2.0 liters of dialysis solution (depending upon patient size) are delivered each cycle by an automatic peritoneal dialysis cycler machine. After the last outflow during the night, an additional exchange is infused by the cycler machine into the peritoneum. The equipment is then disconnected from the patient, and the dialysate remains in the peritoneum for 14 to 15 hours during the day until the next nocturnal cycle (Diaz-Buxo et al. 1981). Combinations of 1.5% or 2.5% dextrose containing peritoneal dialysis solutions are usually used for the nighttime exchanges, while 3.5% or 4.25% dextrose containing solution is used when extra fluid removal is required such as during the daytime exchange. Patient weight is used as the indicator of the need for fluid removal (Popovich et al. 1978) so therapy should be individualized according to the patient’s need for ultrafiltration.

It is recommended that adult patients being placed on peritoneal dialysis or, in the case of pediatric patients, the selected caretaker, (as well as the patient, when suitable), should be appropriately trained in a program which is under the supervision of a physician. Training materials are available from Baxter Healthcare Corporation, Deerfield, IL 60015 USA to facilitate this training.

How is Dianeal with Dextrose Supplied

DIANEAL Low Calcium peritoneal dialysis solutions in AMBU-FLEX III containers are available in nominal size flexible containers with fill volumes as indicated in Table 1.

All DIANEAL Low Calcium peritoneal dialysis solutions have overfills which are declared on container labeling.

Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. It is recommended the product be stored at room temperature (25°C/77°F): brief exposure up to 40°C (104°F) does not adversely affect the product.

Directions for Use

Use aseptic technique.

For complete system preparation, see directions accompanying ancillary equipment.

Peritoneal dialysis solutions may be warmed in the overpouch to 37°C (98.6°F) to enhance patient comfort. However, only dry heat (for example, heating pad) should be used. Solutions should not be heated in water due to an increased risk of infection. Microwave ovens should not be used to heat solutions because there is a potential for damage to the solution container. Moreover, microwave oven heating may potentially cause overheating and/or non-uniform heating of the solution that may result in patient injury or discomfort.

To Open

Tear overpouch down side at slit and remove solution container. Some opacity of the plastic due to moisture absorption during the sterilization process may be observed. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually. If supplemental medication is desired, follow directions below before preparing for administration. Check for minute leaks by squeezing container firmly.

To Add Medication

Additives may be incompatible.

If the resealable rubber plug on the medication port is missing or partially removed, do not use product if medication is to be added.

  1. Prepare medication site.
  2. Using a syringe with a 1 inch long 19 to 25 gauge needle, puncture resealable medication port and inject.
  3. Position container with ports up and evacuate the medication port by squeezing and tapping it.
  4. Mix solution and medication thoroughly.

Preparation for Administration
  1. Place container on table or suspend from support (depending on technique).
  2. Remove protector from outlet port of container. If a continuous fluid flow is noted, discard container.
  3. Attach appropriate solution transfer set to container. Refer to complete directions in hardware manual and/or directions accompanying transfer set.
  4. If the container has not been suspended, suspend at this time.

Discard unused portion.

REFERENCES

  1. Diaz-Buxo, J.A. et al. 1981. Continuous cyclic peritoneal dialysis: a preliminary report. Int Soc Artif Organs 81:157-161.
  2. Diaz-Buxo, J.A. et al. 1983. Observations on inadequate base buffer concentrations in peritoneal dialysis solutions. ASAIO Abstracts 43.
  3. Furman, K.I. et al. 1978. Activity of intraperitoneal heparin during peritoneal dialysis. Clinical Nephrology 9:15-18.
  4. Irwin, M.A. et al. 1981. Continuous ambulatory peritoneal dialysis in pediatrics. AANNT J 8:11-13, 44.
  5. Kim, D. et al. 1984. Continuous ambulatory peritoneal dialysis with three-liter exchanges: a prospective study. Peritoneal Dial Bull 4:82-85.
  6. La Greca, G. et al. 1980. Acid base balance on peritoneal dialysis. Clinical Nephrology 16(1):1-6.
  7. Mattocks, A.M. and El-Bassiouni, E.A. 1971. Peritoneal dialysis: a review. J Pharm Sci 60:1767-1782.
  8. Moncrief, J.W. et al. 1982. CAPD: Are three exchanges per day adequate? AANNT J 9:39-43.
  9. Nolph, K.D. et al. 1981. Considerations for dialysis solution modifications. In Peritoneal Dialysis, eds. Robert C. Atkins et al. Chapter 25. New York: Churchill Livingston.
  10. Popovich, R.P. et al. 1978. Continuous ambulatory peritoneal dialysis. Ann Intern Med 8:449-456.
  11. Potter, D.E. et al. 1981. Continuous ambulatory dialysis (CAPD) in children. Trans Am Soc Artif Intern Organs 27:64-67.
  12. Ribot, S. et al. 1966. Complications of peritoneal dialysis.Am J Med Sci 252:505-517.
  13. Slatopolsky, E. et al. 1986. Calcium carbonate as a phosphate binder in patients with chronic renal failure undergoing dialysis.NEJM 3:315, 157-160.
  14. Twardowski, Z.J. and Janicka, L. 1981. Three exchanges with a 2.5 liter volume for continuous ambulatory peritoneal dialysis. Kidney Int 20:281-284.
  15. Twardowski, Z.J. et al. 1983. High volume low frequency continuous ambulatory peritoneal dialysis. Kidney Int 23:64-70.
  16. Twardowski, Z.J. and Burrows, L. 1984. Two year experience with high volume, low frequency continuous ambulatory peritoneal dialysis. Peritoneal Dial Bull 4:S67.
  17. Vaamonde, C.A. and Perez, G.O. 1977. Peritoneal dialysis today.Kidney 10:31-36.
Table 1
Composition/100mL OSMOLARITY (mOsmol/L) (calc) pH Ionic Concentration & (mEq/L) How Supplied
*Dextrose, Hydrous, USP Sodium Chloride, USP (NaCl) Sodium Lactate (C3H5NaO3) Calcium Chloride, USP (CaCl2•2H2O) Magnesium Chloride, USP (MgCl2•6H2O) Sodium Calcium Magnesium Chloride Lactate Fill Volume (mL) Container Size (mL) Code NDC
Dianeal® Low Calcium (2.5 mEq/L) Peritoneal Dialysis Solution with 1.5% Dextrose 1.5 g 538 mg 448 mg 18.3 mg 5.08 mg 344 5.2
(4.0 to 6.5)
132 2.5 0.5 95 40 1500
2000
2500
3000
5000
6000
2000
2000
3000
3000
5000
6000
5B9715
5B4825
5B9718
5B9901
5B4826
5B9770
0941‑0409‑45
0941 - 0409 - 36
0941 - 0409 - 48
0941 - 0409 - 49
0941 - 0409 - 27
0941 - 0409 - 28
Dianeal® Low Calcium (2.5 mEq/L) Peritoneal Dialysis Solution with 2.5% Dextrose 2.5 g 538 mg 448 mg 18.3 mg 5.08 mg 395 5.2
(4.0 to 6.5)
132 2.5 0.5 95 40 1500
2000
2500
3000
5000
6000
2000
3000
3000
3000
5000
6000
5B9725
5B9727
5B9728
5B9902
5B5202
5B9771
0941‑0457‑45
0941 - 0457 - 47
0941 - 0457 - 48
0941 - 0457 - 49
0941 - 0457 - 25
0941 - 0457 - 28
Dianeal® Low Calcium (2.5 mEq/L) Peritoneal Dialysis Solution with 3.5% Dextrose 3.5 g 538 mg 448 mg 18.3 mg 5.08 mg 445 5.2 (4.0 to 6.5) 132 2.5 0.5 95 40 2500 3000 5B9738 0941‑0463‑48
Dianeal® Low Calcium (2.5 mEq/L) Peritoneal Dialysis Solution with 4.25% Dextrose 4.25 g 538 mg 448 mg 18.3 mg 5.08 mg 483 5.2
(4.0 to 6.5)
132 2.5 0.5 95 40 1500
2000
2500
3000
5000
6000
2000
3000
3000
3000
5000
6000
5B9745
5B9747
5B9748
5B9903
5B5203
5B9772
0941‑0459‑45
0941 - 0459 - 47
0941 - 0459 - 48
0941 - 0459 - 49
0941 - 0459 - 25
0941 - 0459 - 28

Baxter, DIANEAL, AMBU-FLEX, and PL 146 are trademarks of Baxter International Inc.

Baxter Healthcare Corporation

Deerfield, IL 60015 USA

Printed in USA

©Copyright 1981, 1982, 1983, 1984, 1989 Baxter Healthcare Corporation. All rights reserved.


Dianeal with Dextrose (Sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose)
PRODUCT INFO
Product Code 0941-0409 Dosage Form INJECTION, SOLUTION
Route Of Administration INTRAPERITONEAL DEA Schedule
INGREDIENTS
Name (Active Moiety) Type Strength
Dextrose hydrous (dextrose) Active 1.5 GRAM  In 100 MILLILITER
Sodium Chloride (sodium chloride) Active 538 MILLIGRAM  In 100 MILLILITER
Sodium Lactate (sodium lactate) Active 448 MILLIGRAM  In 100 MILLILITER
Calcium Chloride (calcium chloride) Active 18.3 MILLIGRAM  In 100 MILLILITER
Magnesium Chloride (magnesium chloride) Active 5.08 MILLIGRAM  In 100 MILLILITER
Water Inactive  
IMPRINT INFORMATION
Characteristic Appearance Characteristic Appearance
Color Score
Shape Symbol
Imprint Code Coating
Size
PACKAGING
# NDC Package Description Multilevel Packaging
1 0941-0409-45 1500 MILLILITER In 1 BAG None
2 0941-0409-36 2000 MILLILITER In 1 BAG None
3 0941-0409-48 2500 MILLILITER In 1 BAG None
4 0941-0409-49 3000 MILLILITER In 1 BAG None
5 0941-0409-27 5000 MILLILITER In 1 BAG None
6 0941-0409-28 6000 MILLILITER In 1 BAG None

Dianeal with Dextrose (Sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose)
PRODUCT INFO
Product Code 0941-0457 Dosage Form INJECTION, SOLUTION
Route Of Administration INTRAPERITONEAL DEA Schedule
INGREDIENTS
Name (Active Moiety) Type Strength
Dextrose hydrous (Dextrose) Active 2.5 GRAM  In 100 MILLILITER
Sodium Chloride (Sodium Chloride) Active 538 MILLIGRAM  In 100 MILLILITER
Sodium Lactate (Sodium Lactate) Active 448 MILLIGRAM  In 100 MILLILITER
Calcium Chloride (calcium chloride) Active 18.3 MILLIGRAM  In 100 MILLILITER
Magnesium Chloride (magnesium chloride) Active 5.08 MILLIGRAM  In 100 MILLILITER
Water Inactive  
IMPRINT INFORMATION
Characteristic Appearance Characteristic Appearance
Color Score
Shape Symbol
Imprint Code Coating
Size
PACKAGING
# NDC Package Description Multilevel Packaging
1 0941-0457-45 1500 MILLILITER In 1 BAG None
2 0941-0457-47 2000 MILLILITER In 1 BAG None
3 0941-0457-48 2500 MILLILITER In 1 BAG None
4 0941-0457-49 3000 MILLILITER In 1 BAG None
5 0941-0457-25 5000 MILLILITER In 1 BAG None
6 0941-0457-28 6000 MILLILITER In 1 BAG None

Dianeal with Dextrose (Sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose)
PRODUCT INFO
Product Code 0941-0463 Dosage Form INJECTION, SOLUTION
Route Of Administration INTRAPERITONEAL DEA Schedule
INGREDIENTS
Name (Active Moiety) Type Strength

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